Infertility can be treated in many ways. We offer a wide range of possible treatments, ranging from the most basic, to highly specialised medical techniques. However, our philosophy is that the patients should be treated only with methods that are really necessary and beneficial.
The method of in-vitro fertilisation, where the sperm is left alone to spontaneously merge with an egg, has been enhanced by additional methods to reach higher success rates. That is the reason why it is standard for IVF CUBE to use the ICSI method, Assisted Hatching (AH), prolonged cultivation and vitrification of the remaining embryos. Thanks to these additional methods we are able to reach over 84% success rate.
With the ICSI method the sperm is put into the egg cytoplasm. The ICSI method is performed with the help of a microscope equipped with multiple enlargement glass, together with the use of a micro syringe. The ICSI method is used at IVF CUBE as standard procedure because it dramatically increases the success rate.
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A 5 day embryo cultivation process, from the egg fertilization until the embryo transfer at the blastocyst stage. Embryos can be transferred earlier, for example on day 3, however the blastocyst culture gives us a higher chance of the embryo attaching to the endometrium. It also allows a longer window to choose the best morphologically appropriate embryo for transfer. If applicable, IVF CUBE uses the blastocyst culture method for all treatments.
A micromanipulation method in which the protein cover (pellucid zone) of the egg is opened by laser. The hatching process is then facilitated by the opening of the cover in the inner cellular part so that the embryo can easily get through the pellucid zone. Assisted hatching is performed on all the available embryos on day 4, when embryos reach the compact stage.
A method of quick freezing (of embryos, eggs, sperm). Quick freezing is much more compatible to the human cells, because it prevents any crystals forming and increases the safety of the cells with further unfreezing and usage in the following IVF cycles. Vitrification is a standard part of all cycles performed at IVF CUBE.
Sperm cells are placed on a disposable chip where they are allowed to actively migrate through the passage of various micro-barriers and a membrane into the outlet chambers. During this proces, viable healthy sperm cells are separated and collected into the outlet chambers similarly as they would do naturally when reaching an egg cell in a female reproductive system.
The method is based on natural sperm selection. Selected sperm cells have better motility, genetic quality and morphology. This method increases the treatment success by up to 20-25%.
In this therapy plan, the patient is on minimal hormonal stimulation. Patients take the medication orally, and minimal stimulation injections may be added throughout the treatment process. The egg maturation is then enhanced by the one time application of a injection 36 hours before the egg collection.
This treatment is performed during regular ovulation. The partner’s sperm is, after previous preparation in the andrological laboratory, inserted into the female uterus with the help of a narrow catheter. The IUI method is the least invasive, usually completely pain free with minimal risks.
